Screening and Selection of Anti-Clostridium Monoclonal Antibodies Using the ProteOn™ XPR36 System





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Published on Oct 8, 2012

For more info, visit http://www.bio-rad.com/yt/6/proteonxpr36
Clostridium difficile infections are increasing in incidence, severity, and mortality: rapid identification of virulent strains is essential for preventing their spread. In this webinar, Dr Carlotta Chiappa presented how the ProteOn XPR36 system played a key role in screening and selecting specific mAbs for the development of a chemiluminescent immunoassay to detect Clostridium difficile antigens. The flexibility in assay orientation options provided by the ProteOn system allowed multiple analyses on hybridoma supernatants to identify the best candidates in terms of affinity and performance prediction.

Carlotta Chiappa, PhD
Antibody Development Unit
DiaSorin Research Center, Italy


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