 This study demonstrated the feasibility of 3D printing polylactic acid, PLA, scaffolds and their potential applications in craniofacial implants. The scaffolds had a porosity of 73% with an average pore size of 450 microns and an average scaffold fiber thickness of 130 microns. The average compressive modulus was 244 MPa and the scaffolds generated an electric potential of 25 MV upon cyclic slash repeated loading. The crystallinity reduced from 27.5% to 13.9% during the 3D printing process. The hydrolytic degradation was minimal during a 12-week period. Osteoblast-like cells did not attach to the uncoded scaffold but attached well after coating the scaffold with fibrinogen. They then proliferated to cover the entire scaffold by day 14. This study demonstrates the potential of 3D printing PLA scaffolds for craniofacial implants. This article was authored by Devakar Karant, David Pulio, Dolph Dawson, and others. We are article.tv, links in the description below.