 The study aimed to develop a novel drug delivery system using titanium dioxide, TiO2, nanoparticles coated with polyethylene glycol, PEG, and loaded with 2-methoxyestratio, 2-mi, which was characterized through IR and Raman spectroscopy, revealing effective adsorption capability for drug delivery. This article was authored by Andrea Leon, Patricia Ryukwin, Carolina Garan, and others.