 The COVID-19 pandemic has caused significant disruption to the social, economic and health systems of Thailand. To combat the spread of the virus, the Thai government implemented a nationwide lockdown protocol, which was later supplemented by a vaccination program. However, initial shortages of vaccines and a lack of available options led to further complications. Research is now being conducted to monitor the progress of the population's immunity levels, while also providing recommendations for adults who have not yet received their fourth booster dose. Despite these efforts, challenges still exist, such as low levels of vaccine literacy among the unvaccinated and under vaccinated populations, as well as hesitation from some individuals to get additional booster shots. In order to reach herd immunity, collaboration between multiple stakeholders will be necessary, along with improved health promotion campaigns targeting vulnerable populations, such as older adults and those living in rural areas.