 This study examined the metabolic profile of patients with chronic kidney disease and gallbladder disease who were undergoing treatment at a spa resort. The results showed that patients with high blood pressure had higher levels of sodium and uric acid in their urine, lower levels of phosphorus and magnesium, and higher electro-kinetic activity compared to those with normal blood pressure. This suggests that these patients may have different metabolic profiles than those with normal blood pressure. This article was authored by Natalia Koziakina, Yulia Vovchina, Natalia Voroniksenchenko, and others.