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Published on Feb 19, 2014
Table of Contents: 00:09 Lecture 1.3: Nanobiosensors Basic Concepts: Types of Biosensors 01:47 Outline 03:08 Introducing the sensor 04:33 Capture of molecules on sensor surface 08:47 Nanoscale biosensors: Labeled approach 11:32 Three types of label-free sensors 15:22 Sensitivity are similar 17:11 Diversity of biosensors 18:03 Nanobiosensors have high sensitivity 19:55 Sensitivity Gain: Geometry of Electrostatics ? 23:18 Sensitivity Gain: Geometry of Electrostatics ? 24:44 Geometry is Important, but exactly how ? 26:21 Conclusions
This course provides an in-depth analysis of the origin of the extra-ordinary sensitivity, fundamental limits, and operating principles of modern nanobiosensors. The primary focus is the physics of biomolecule detection in terms of three elementary concepts: response time, sensitivity, and selectivity. And, it potentiometric, amperometric, and cantilever-based mass sensors to illustrate the application of these concepts to specific sensor technologies.