 In this study, the authors developed a novel approach to produce silver-decorated mesoparasilica nanoparticles, the MSNs. These particles are made from a biocompatible flavonoid extract, which acts as a reducing agent and non-sufactant template. The resulting MSNs exhibit excellent antimicrobial activity against both gram-positive and gram-negative bacteria, as well as fungal species. Additionally, they show minimal cytotoxic effects when tested with human cells. This suggests that the silver-decorated MSNs may be useful in a variety of biomedical applications. This article was authored by Milod or Bossi, Razia golezadeh, Seidriza carci, and others.