 This study examined the effectiveness of various coatings on endotracheal tubes to reduce biofouling and friction-related damage to the tissues. The researchers developed a test setup to compare the performance of these coatings under controlled conditions. They found that covalently bonded coatings made from purified pig mucin were most effective at reducing biofouling and minimizing tissue damage. This study provides valuable insight into how coatings can be used to improve the safety and efficacy of endotracheal tubes. This article was authored by Bernardo Miller-Noronho, Samay Niker, and Oliver Lyleg.