 This study aimed to optimize the design of a single-effect evaporator used in the production of agave syrup from agave salmiana groan in Las Mondas, Coahuila, Mexico. The evaporation process was simulated using response surface methodology, RSM. This allowed us to determine the optimal conditions for the evaporation process, including the amount of raw material fed into the evaporator, S, and the temperature of the raw material, T. These parameters were then used to calculate the amount of steam needed, Q, and the energy required, Q, to achieve maximum syrup yield. This article was authored by Diogenes Daniel Avalolara, Ana Lu Rubio Rios, Lucero Rosales Marines, and others.