Studying Small Molecule-Kinase Interactions Using Multiplexed SPR




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Published on Jan 16, 2013

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In this webinar, Tsafrir Bravman of Bio-Rad Laboratories continues the SPR Expert series by presenting a case study using the ProteOn XPR36 system to study the interactions of two protein kinases, p38 and ERK2, with a panel of small-molecule inhibitors conducted in collaboration with Chugai Pharmaceuticals, Japan. The results of their screening program are presented and discussed, followed by an overview of best practices for small-molecule assay configuration and particular considerations for this system.

Tsafrir Bravman, PhD
Manager, SPR Applications Group
Bio-Rad Laboratories


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