 Biologically inspired materials have emerged as promising alternatives for tissue engineering and regenerative medicine. These materials are designed to mimic the properties of natural extracellular matrices, providing cells with a range of biochemical and biophysical cues. They also possess mechanical adaptability, microstructure connectivity, and inherent bioactivity, making them ideal for the development of living implants. Recent advancements in the fabrication of these materials include the use of novel techniques to create porous structures, as well as the incorporation of biological molecules and proteins to enhance their functionality. Furthermore, these materials have been used to successfully treat a variety of diseases and injuries, demonstrating their potential for clinical application. Despite these successes, there remain several challenges to be addressed before these materials can be widely adopted in clinical settings. This article was authored by Shui Liu, Jian Ming Yu, Yang Chang'an, and others.