 I'm super optimistic about the future just because we are seeing some results that we have not seen before with immunotherapy and the interplay where people with stage four disease and some situations such as melanoma or lung cancer, if they have the right series of mutations, we're seeing a long-term survivor, so that's been kind of a game changer recently. What's better? If we have a single lung tumor, should we treat it with stereotactic radiation or should we remove it surgically? And my argument is if we treat it with radiation, the cells as they go through the process of apoptosis actually kind of lice open up, the interior contents create antigens that are recognized by the immune system and so that it can make the immune system kind of primed and then immunotherapy after radiosurgery may be able to affect the development of metastatic disease. Super, super exciting.