 This is Dr. Ross and Apostolof to introduce you shortly to the activities of the BioXL Center of excellence. So, Dr. Apostolof, please be welcome. Thank you, Anela. Do you hear me well? Do you hear me? Yes. Thank you. Yes. So, thanks everyone. It's really great to see this event in place. Big thanks to the whole organization for putting this together. This is a very important training type of training for biomolecular simulations. I hope that all of the students attending this this week will find it very useful. I'm leading BioXL Center of excellence, one of the organizing locations of the event. I'll give you a little bit about the center, what we do. You'll learn about some of the services that we offer, which might be very useful in your work. And we are also open towards the communities to help each other and to drive forward science, providing advanced applications and support services. So, as Elini already discussed, we are already at the stage inside where computers and the methods that we are used to model and simulate molecules are at a stage where it's ready for full-scale production and search for new drugs. And this school being a preschool, you are probably familiar, that places the largest demand organization in Europe, which provides access to supercomputers. And you have big possibilities in your research work to use all of these machines, TR0, these machines in Europe, that give you a true power to learn simulations and drive forward your research work. But as you have probably experienced, it's not that to use effectively such large machines. The software is getting more and more very powerful with a lot of features, but making the best use of it. It takes some skill and a lot of knowledge. It's our hope that you learn a lot about this during this. So BioXL Center of Excellence was established ago as an opportunity to support life science researchers in their work by providing high quality and user-friendly software, not only providing the tools, but increasing the expertise and the skills of researchers and bringing the community together. The center is now in the thin face. We're looking for a third one to continue for at least for several more years. BioXL is working with the core developers of several big important machines that are extensively used in drug design and molecular modeling. I will tell you a little bit about them and learn how to use most of the core codes in this week. We developed the software that also workflow solution on them. Around the products we have extensive services which are provided to the community to support with their training and increasing the expertise. Here's a very brief overview of the main code which we work with. Gromach's Haddock and PMX you will learn about the best way to use them tomorrow and on when. Gromach's Require Dynamic Simulations, High Relative Modeling and PMX for Free Energy Calculations. We also were developing an interface that couples MD codes with QM codes for those of you who are doing hybrid QM-MM study for example in Zimatic Create. We also do a lot of work on workflow solutions, particularly with the BioXL building blocks, BioBB frame. So in addition to all the software, as I mentioned, a lot of our work is towards the communities to provide support with their usage. Some of you might have already visited task.bioxl.eu where we provide the community forums. So being monitored by the core developers of the applications, there you will find help and probably answers to most of your questions with all of the applications that are developed in the center. We have been running for many years webinar series at bioxl.eu slash webinars and in our YouTube channel you can find recordings for webinars covering a lot of different and important software applications, not only those developed by xl but also once. We also cover a lot of methods that are gaining attention and are very well developed in the field. Success stories that are notable, it's a great resource for self-study and training. We regular training events, this week's event is one of them. I would recommend that you your regular website and you subscribe to our newsletter to learn about new activities. We launched recently a documentation website dot.eu where you can find a lot of best practice guides which are really important to consult with to research. They will be very helpful in your work and on this side we have docs.buxl.eu, there's also links to tutorials etc. Also it's a documentation that will be very helpful in your work. As I mentioned we work a lot on training and I want to highlight that our training program is based on the competency profiles meaning that for different teachers say novice who come from experimental background and are just starting with computer have different needs from those who are already power users that have been using the tools for many years. So we have these different profiles that you can benchmark yourself and what is needed more to learn, where to find information and so on. We organize events year round and mostly have very good and excellent feedback from most of the attendees. I want to highlight one of our flagship conference which is taking place in October. The registration deadline is this week. Visit our website, have a look at the speakers. It's a really selection of keynotes and presenters. You will find invaluable information there so I highly recommend you consider attending. It's a virtual also so it's very easy for everyone to attend. Finally, I want to highlight that we are also in the process of launching a another partner organization to COE, Buxl Enterprises which will be an additional vehicle support arm that will help us expand the network, strengthen the community, increase the collaborations between academia, industry and overall long-term support to the communities. So it's something that you might be interested in not knowing about and maybe it's something we can work together. So this was all from me. I recommend you subscribe to our newsletter. It comes usually once a month. There's very low traffic. You will learn about upcoming important events, webinar presentations. It's a very good way to keep in touch progress of the work done in the center. With that, I want to wish everyone a very successful week. I hope the program we've prepared for you will be very useful. You will learn a lot and you will apply in your research all the techniques that you look here and do a great response to. Thanks everyone. That's all from me. Thank you. Are there any questions? We'll wait a little bit because there seems to be some delay and a question pops up in the chat. I'll be happy to take questions also offline later. Okay. Our main work is to enable efficient HPC usage. But in order to make best use of HPC, you should also know how best to use the programs even if you're using them on a desktop. And to understand the science and the methods, the algorithms that are the basis for the calls. So, yes, it's possible.