 The use of biocompatible formulations containing 2-hydroxyethyl, methacrylate, hema, and 2-methylol-arxyethylphosphorylcholine, MPC, can prolong the drug residence time in the subconjunctival space after surgery to treat glaucoma. This can be achieved by preparing drug-releasing discs with varying amounts of these components. The ratio of bound water, WB, to free water, WF, increases as more MPC is added, resulting in higher swelling ratios. Additionally, the optimal balance between water content, SR, and mechanical strength are found at 10% MPC, WW, hydrogels. Water alcohol mixtures are also examined to facilitate loading of poorly soluble drugs, which show greater hydrogel swelling than either water or alcohol alone. Furthermore, water, ethanol, 1,1, mixtures increase the drug loading capacity compared to methanol alone. Finally, dexamethane is loaded into hema MPC, 10%, discs using either water, ethanol. This article was authored by Afmal Sohani, Sahawad, Peng T-Shaw, and others. We are article.tv, links in the description below.