 Good morning everyone. I'm Dr. Sundin Jain from Maharshi Mercantile Medical College, Milana. Today I'm going to be presenting a rare scenario of a neuroendocrine tumor in the gallbladder. Neuroendocrine tumors are one of the rarest tumors which accounts for only 0.2% and in them also 2% of the tumors are of gallbladder tumors which is usually an incidental findings. Hence to distinguish gallbladder tumors from neuroendocrine tumor of the gallbladder it is important to correlate radiological imaging from histopathological and immunochemistry study. So today I'm presenting a case of a 27-year-old woman presented with upper abdominal pain since one month which was insidious in onset, non-progressive and with vomiting. There were no aggravating or relieving factors. The objectives of my case presentation are to determine the imaging features of gallbladder, neuroendocrine tumor, second correlation of the radiological imaging features with histopath and immunochemistry. First of all NCCT abdomen was butan which showed the homogenous isodense mass noted in the gallbladder which measured approximately 6.8 into 8.7 into 7.4 centimeter and we can see there are no calcification on necrotic areas present in it. After that on contrast in arterial phase we see that the mass shows homogenous enhancement in the arterial phase and there are multiple lymph nodes present in the pre-aortic, pari-aortic, peripentriatic region. In such societal images also we can show there is homogenous enhancement of the gallbladder mass. In coronal images also there's homogenous enhancement of the gallbladder mass. In venous phase also we can see the mass shows homogenous enhancement with lymph nodes in all the periportal renal and pari-aortic regions. Here we can see the fundus of the gallbladder which is diffusely thickened and irregular walls. However there is mass which shows homogenous enhancement. So we came to a diagnosis that this is a well-defined homogeneously enhancing mass in the gallbladder fossa and it was a sustainable magnet etiology. The possible differential diagnosis to be considered work, edinocarcinoma and lymphoma. Therefore, USG-guided biopsy and HP correlation were advised. On biopsy, we could see atypical cells of intermediate size having around oval shape with hyperchromatic nucleus and scantycytoplasm and no evidence of lymphoid tissue was seen in the section. Hence it was suggestive of poorly differentiated neuroendobrine tumor. In immunohistochemistry it was the new plastic cells were stained with synaptoptoficin and CD5-6 and Ki6-7 index was up to 90%. On discussion, as we have discussed already neuroendocrine tumors are rare entity that accounts for only 0.5% and in which gallbladder tumors account for only 2.1%. Neuroendocrine tumors are a derivative of multi-potent stem cells slash neuroendocrine cells in the intestinal metaplasia which occurs in chronic inflammation such as scolelythiasis and it commonly occurs in an age group of 27 to 75 years with a female preponderance. Most commonly it is involved in gastrointestinal tract that is ileum, jejunum and pancreas, liver and gallbladder are rarely involved. It may also involve palmini system and thyroid and the patient presents with big symptoms like pain, abdominal nausea in the early stages of tumor and with jaundice and weight loss in late stages. Histologically it is graded into three low-grade, intermediate and high-grade on the basis of proliferative index of Ki6-7. Therefore, it is very essential to diagnose and differentiate other gallbladder tumors from the neuroendocrine tumors which can only be done on correlating radiological imaging findings with a histopath and immunochemistry chemistry study. Multimodal therapy such as surgical resection, chemo and radiotherapy can increase survival rate. However, the prognosis is not good for the neuroendocrine tumors. To summarize, this case study shows that the gallbladder neuroendocrine tumor is a very rare tumor. The clinicians should raise a suspicion and consider it as a differential diagnosis for young patients who present with abdominal pain in middle-aged females specially and should relate their radiological findings with the histopath and immunochemistry study. Thank you.