 Diabetes is a serious health condition that affects millions of people worldwide. It is characterized by high levels of sugar in the blood due to insulin resistance or lack of insulin production. One of the most dangerous complications of diabetes is diabetic nephropathy, DN, which is a progressive kidney disease caused by chronic hyperglycemia. Early detection of DN is important because it can lead to end-stage renal disease, ESRD. The presence of microalbuminuria, a marker of early DN, can be detected through a simple urine test. In this study, researchers examined the expression of vascular endothelial growth factor, VEGF, in various stages of DN and found that it is associated with several clinical and histopathological parameters. This suggests that VEGF may play a role in the development of DN and should be further investigated.