 The Allen Institute Minescope OpenScope dataset provides valuable insight into the differences between apical and somatic processing and plasticity in visual cortical pyramidal neurons. It contains high-quality 2-photon calcium imaging data from both the apical dendrites and cell bodies of these neurons, which was collected over multiple days in a wake, behaving mice. This data enables researchers to study the changes in the responses of these neurons over time, providing important information about the roles of apical and somatic processing and plasticity in neural networks. This article was offered by Colleen J. Gillan, Jerome Alecog, Jason Epina, and others.