 In this study, researchers analyzed the differences in gene expression between corneas of patients with Fux entothelial corneal dystrophy, FECD, and those of healthy individuals. They found that many genes were differentially expressed, suggesting that oxidative stress and apoptosis may play a role in the development of FECD. Additionally, they identified several pathways associated with ECM deposition, which could provide insight into potential therapeutic targets. This article was authored by Totsiya Nakagawa, Yuichi Tokida, Mosoko Zinokono, and others.