 This study investigates the significant contributions of coping, resilience, personal characteristics, and health behaviors on the emotional well-being of pharmacy students during the COVID-19 pandemic. The results show that higher levels of resilience, greater use of coping strategies, and identifying as Hispanic are significant predictors of emotional well-being in this sample, N equals 104. The study suggests that pharmacy programs should cultivate an environment that supports the emotional well-being of their students by encouraging healthy coping behaviors and bolstering personal resilience to better prepare them for providing frontline patient care in the future. This article was authored by Andrea V Fuentes, PharmD, Robin J. Jacobs, PhD, MSW, MS, MPH, Eric I.P., PharmD, APH, BCPS, CSCS, CDE, FCSHP, and others.