 Complex i is a mitochondrial protein complex that plays a key role in the production of adenosine triphosphate, ATP, through oxidative phosphorylation. It is composed of 43 subunits, many of which are highly conserved between humans and flies. In this study, researchers isolated complex i from Drosophila melanogaster and determined its structure. They found that it has a similar structure to complex i in humans, but with some differences. For example, one subunit was found to be more similar to human subunit in Doofah 3 than previously thought. Additionally, they discovered that the complex can exist in two different states, one of which resembles the ready-to-go active state seen in humans, while another resembles the deactivated state. This information will help scientists better understand how complex i works and how it may be used as a model system for studying other proteins. This article was offered by Ahmed Noe Adjib in Jecheng, Alvaro Sanchez Martinez, and others. We are article.tv, links in the description below.