 This thirteen-year-old female is a pupil who presented with an edematous lesion involving the right hand. An FNA aspirate was positive for M. ulcerans. This is a category 2 buruli edema lesion. Treatment with streptomycin refampicin was commenced according to the WHO recommendations. Because of the irregular dimensions of this lesion, it was difficult to trace the outline. However, the clinical response was monitored with serial photography. And we see that at two weeks there was a complete regression of the edema. However, treatment was continued for eight weeks according to the WHO recommendations. And this is to ensure that the organisms are completely eradicated with the antibiotic treatment.