 The study found that flavonones are promising candidates for topical anti-cancer therapy due to their ability to inhibit tumor growth and their high permeability into the skin. Furthermore, they can be formulated into biodegradable polymers to increase their stability and prolong their effectiveness. This article was authored by Paula Bustos-Salgado, Berenice Andrade Carrera, Valeri Dominguez Villegas, and others.