 The Indiana CTSS Reciprocal Innovation Program leverages a 30-year partnership between Indiana University in the U.S. and Moe University in Kenya to promote mutual learning and benefit through a bidirection, co-constituted, and iterative exchange of ideas, resources, and innovations. The program hosts annual meetings, supports pilot grants for projects with reciprocal exchange and benefit, and produces educational and training materials for investigators, with the goal of redefining global health for shared well-being at a global scale. This article was authored by Thomas Jesus, Rishika Chahon O'Brien, Michael L. Scanlen, and others.