 The Mayo Clinic Center for Clinical and Translational Science and the Yale Mayo Center for Excellence in Regulatory Science and Innovation delivered a pilot course. The course used didactic, case-dash and problem-based learning sessions to expose students to regulatory science concepts. Students reported learning an incredible amount, 7.19, 36.8%, or a lot, 9.19, this was reflected in individual coursework and their course evaluations. This article was authored by Alexandra J. Greenberg-Warisek, Catherine E. Cornelius, Luz Cumbagasia, and others.