 This study investigates the therapeutic effects of black soldier fly larvae, BSFL, and their fermented form, in conjunction with a strain of lactobacillus plantarum KCCM12757P, on chronic colitis-induced mirine models. The results show that he high underscore LP, the fermented BSFL, significantly reduced disease activity index, inflammatory cytokines, an improved intestinal barrier function, gut microbial communities, and gene expression in the NF Kappa B signaling pathway. Therefore, he high underscore LP can be used as a dietary supplement and pet food to alleviate colitis. This article was authored by Suk Jun Sun, RM Han, Mi Jong Sung, and others.