 The antimicrobial resistance, AMR, crisis is a growing global problem caused by the evolutionary response of microbes to widespread antimicrobial use, the large and connected human population, and the extensive use of antimicrobials. To manage this crisis, reducing the applied selective pressure on microbes by radically reducing global antimicrobial use is necessary. In addition to current measures, a comprehensive education program is required to change the public paradigm of antimicrobial usage from first-line treatment to last resort when all other options have failed. This article was authored by Carolyn and Michael, Daily Domini House, and Maurizio Elabate. We are article.tv, links in the description below.