 MYH9-related diseases, MYH9-RD, are clinically represented by thrombocytopenia, large platelets, protonaria and various degrees of renal dysfunction. We present a 25-year-old male with thrombocytopenia, large platelets, renal dysfunction and protonaria. Gene sequencing of whole exons of MYH9 gene confirmed the diagnosis of MYH9-related disorder and revealed single nucleotide polymorphisms, SNPs, in the introns 13, RS-3752462, and 14, RS-2413396, and a mutation in exon-26 of MYH9 gene. Our results supported the possibility of non-coating SNPs involvement in the pathogenicity of the MYH9-RD disease and successful renal transplant in this patient. This article was authored by Sipitas and Mini Vaheid, Barham Nicknafs, Hamid Nosehad and others. We are article.tv, links in the description below.