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Ghosh Alzheimer's

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Published on Oct 1, 2012

Arun Ghosh, Purdue's Ian P. Rothwell Distinguished Professor of Chemistry and Medicinal Chemistry and Molecular Pharmacology, designed a new molecule to treat Alzheimer's disease. The molecule is a highly potent beta-secretase inhibitor with unique features that ensure it goes only to its target and does not affect healthy physiological processes. A representation of the inhibitor molecule attached to beta-secretase is shown. The beta-secretase molecule is depicted through a gold ribbon diagram that shows the twists and folds of the protein. The colored spheres represent the atoms of the inhibitor molecule. Andrew Mesecar, the Walther Professor in Cancer Structural Biology and Deputy Director of the Purdue University Center for Cancer Research created the animation. (Purdue University movie/Andrew Mesecar)
http://www.purdue.edu/newsroom/releas...

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