 This study examined the relationship between climate variability and dengue incidence in Bangladesh. It found that temperature was positively associated with the annual incidence during the late winter months, January through March, while it was negatively associated during the early summer, April through June. This suggests that an optimal minimum temperature for mosquito growth may be around 21 to 23 degrees Celsius. Additionally, this study could help inform public health officials about the potential for future dengue outbreaks in neighboring countries such as northern India and southeast Asia. This article was authored by Emperor Hossain, Wenzhou, Chowren, and others.