 This report describes the methods and timelines for ethical and regulatory review processes of herbal trials in Zimbabwe, highlighting key issues raised and approval times that range between 8 and 72 weeks. The study was registered prospectively on August 3, 2011 with clinical trials.government, NCT 01410058. This article was authored by Sitsi G. Manera Penduka, Charles C. Maponga, Gene D. Morse, and others.