 This meta-analysis assesses the effect of ongoing statin treatment on susceptibility to influenza virus infection and mortality among flu-vaccinated and unvaccinated patients. The results show that statins are associated with a reduction in influenza prevalence, or equals 0.85, 95% Ci, 0.73 to 0.99, P equals 0.040, but not with susceptibility to influenza infection in distinct communities of either vaccinated or unvaccinated subjects. Additionally, the use of statins among patients with influenza was associated with a reduced mortality, or equals 0.68, 95% Ci, 0.56, 0.82, P less than 0.001, which was confirmed for both 30-day mortality since influenza infection diagnosis, or equals 0.61, 95% Ci, 0.47, 0.80, P less than 0.001, and for up to 90-day mortality, or equals 0.74, 95% Ci, 0.55, 1.00, P equals 0.042. These findings suggest that statins may have a potential role as adjunctive therapy in patients with influenza infection, but further research is needed to confirm these results and define the optimal dosage and duration of treatment. This article was authored by Amir Vahidi and Azimi, Massimo Armanorino, Sajat Shojay, and others. We are article.tv, links in the description below.