 Welcome to this course on mycobacterium ulcerans infection, commonly referred to as Buruli ulcer. This course has been designed for medical students, practicing doctors, and field workers who wish to learn more about the disease. In this course, you learn about the general aspects of the disease, including what causes the disease, where you can find it, and then the series of cases explaining the different forms of the disease to help you in making a good clinical diagnosis. There is an animation explaining the pathogenesis of the disease, and a series of videos explaining how to obtain samples for laboratory diagnosis. Finally, there are a series of cases explaining all the difficult or different issues you are likely to encounter in clinical practice. At the end of this course, you should be able to accurately make a clinical diagnosis, take samples to confirm the disease, and manage the disease properly.