 This study found that lung cancer is the leading cause of cancer-related deaths globally, with an estimated 2.2 million new cases and 1.8 million deaths expected in 2020. In the United States, the incidence of lung cancer has decreased over time, while it has increased in China among those aged 50 to 59. Tobacco control measures and improved screening are needed to reduce the burden of lung cancer. This article was authored by Chao Li, Xiaoyuan Lei, Li Ding, and others.