 Gastric cancer is a major public health concern worldwide, particularly among men over age 60. It is the fifth most common type of cancer and the third leading cause of cancer-related deaths. The incidence and mortality rates vary significantly depending on geographic location and the presence of helicobacter pylori, H. pylori, bacterial infection. Recent advances in treatment and prevention strategies have helped reduce the number of cases, but there is still much work to be done. Genetic testing is helping to identify individuals at higher risk for developing this form of cancer, allowing for early detection and improved outcomes. Additionally, lifestyle changes such as quitting smoking, eating a healthy diet, and exercising regularly can all help reduce the risk of developing gastric cancer. This article was authored by Prashant Rala and Adam Barsuk.