 Abstract background neuro-inflammation is a key pathological feature of a wide variety of neurological disorders, including Parkinson's, multiple sclerosis, Alzheimer's, and Huntington's disease. Current treatments for these disorders are primarily symptomatic, but there is a growing interest in developing new therapeutics that target the underlying neuro-inflammatory processes. Marine invertebrates, such as corals, sea urchins, starfish, sponges, and sea cucumbers have been found to contain a wide variety of biologically active compounds with potential therapeutic properties. These compounds target various key proteins and pathways in neuro-inflammation, including 6-hydroxidopamine, OHDH, caspase, 3 and caspase, 9, P act, P ERK, P, P38, acetylcholinesterase, Ake, amyloid beta, A, HSF1, alpha, cynocline, cellular prion protein, advanced glycation end products, ages, para. This article was authored by Baxia Revai and Abtkaka Umar. We are article.tv, links in the description below.