 This case study reports on a patient who was diagnosed with idiopathic nodular glomerulosclerosis ING, a rare condition associated with heavy tobacco smoking, chronic hypertension, obesity, and insulin resistance. The patient had no prior history of diabetes or heavy smoking, but did have a history of marijuana use. This case suggests that marijuana may increase the risk of developing ING. This article was authored by Mary Mollie, T-Bore Fulop, Sohail Abdul Saleem, and others.