 Network Pharmacology is a new approach to studying traditional Chinese medicine, TCM. It has been applied to TCM research to analyze drug combinations, predict targets, and study toxicity. Several databases and tools are available for TCM research, and some of them have been evaluated. Future studies should focus on the microbiome and TCMs to better understand and treat microbiome-related diseases. This article was authored by Ruan Zhixiang, Xue Zhu, Hong Bai, and others.