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Mapping Evolutionary Trace results from a ranks file to a PDB chain in PyMOL using PyETV

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Uploaded on Jun 24, 2010

Summary: PyETV is a PyMOL-based graphical user interface for viewing, analyzing and manipulating functional site predictions on protein tertiary or quaternary structures. Starting from the Evolutionary Trace (ET) server output, namely ranks of relative functional importance for every amino acid in a protein, PyETV maps these rankings onto the structures of the chains of a complex. This provides a convenient, high quality graphics platform for viewing evolutionarily important parts of a protein complex, and integrating them with other tools provided by PyMOL in order to guide analysis and bioengineering to the most functionally relevant part of a protein. PyETV is a downloadable PyMOL plugin written in Python.
Availability: The PyETV module and installation instructions may be found at:
http://mammoth.bcm.tmc.edu/traceview/...

Reference: Lua RC and Lichtarge O.
PyETV: A PyMOL Evolutionary Trace viewer to analyze functional site predictions in protein complexes
Bioinformatics 2010; doi: 10.1093/bioinformatics/btq566

Thank you to W. L. DeLano for PyMOL.
DeLano, W. L. (2002). The PyMOL Molecular Graphics System. DeLano Scientific, San Carlos, CA.

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