 This study developed a novel electrochemical biosensor based on cobalt thalocyanine, COPC, nanorods with graphing quantum dots, GQDs, for the simultaneous detection of dopamine, DA, and uric acid UA. The GQDs incorporation on COPC nanorods with partial and stretching significantly enhanced the electrocatalytic activity and promoted the electron transfer rate. The resulting sensors showed low detection limits of 21 nanometers for DA and 145 nanometers for UA, which were successfully detected in human urine samples. The excellent performance of the sensor suggested as a promising and potential candidate for electrochemical sensors to detect both DA and UA selectively. This article was authored by Bo Wu, Min Zhongli, Rajendran Ramachandran, and others.