 This study aims to map the existing evidence on digital health professions education and identify gaps and research priorities to enable robust and relevant research in this field. The study searched for systematic reviews on digital education of practicing and student health care professionals, identified 77 eligible reviews, and mapped the empirical findings and research recommendations against a newly developed conceptual framework. The results revealed that most reviews focused on health professions education in general, surgery, and nursing, and assessed participant skills and knowledge. The study identified 61 unique questions for future research in these areas, which map to framework domains of education, context, infrastructure, learners and research. Overall, the study highlights a diverse and comprehensive research agenda in digital health professions education, with more evidence from low and middle income countries needed. This article was authored by Lorraine Tudorkar, Selina Poon, Bonemint Q, and others. We are article.tv, links in the description below.