 The study investigates the use of thiaflavin T that to detect amyloid fibrils in Alzheimer's disease and prion diseases and examines the relationship between that concentration and amyloid formation as well as the effect of that on aggregation kinetics. The results show that that fluorescence correlates linearly with amyloid concentration over a range of that concentrations and that the maximal fluorescence signal is observed at that concentrations of 20-50 backslash U2005M for the three proteins investigated. The study also finds that that has little effect on aggregation at concentrations of 20 backslash U2005M or lower, but may affect the shape of aggregation curves at higher concentrations. This article was authored by Christine Shueh, Tiffany Yu and Lin, Dennis Chong, and others.