 Tissue engineering, TE, has made significant progress over the last few decades, with advances in the development of 3D scaffolds and hydrogels providing a platform for the regeneration and reconstruction of damaged tissues. These scaffolds and hydrogels can be composed of naturally occurring or synthetically produced materials, and can be tailored to meet specific needs. Additionally, these materials can be combined with bioactive molecules, genes, and cells to create a more robust environment for tissue growth and repair. This combination of materials and components provides a strong foundation for the development of functional engineered tissues, which can then be implanted into the body for successful regeneration. This article was authored by Sandra Pina, Viviana P. Ribeiro, Katerina F. Marquez, and others.