 This systematic scoping review aims to identify potential barriers to iDonation from patients who die in hospice and palliative care settings and to provide an up-to-date view of the current practice underpinning offering the option of iDonation to dying patients and their family members. The review retrieved 13 articles from the global literature, indicating that 542 patients could potentially have donated their eyes. Key barriers include reluctance among healthcare professionals to raise the option of iDonation and lack of awareness about donation options and eligibility among patients and family members. Additionally, there is a lack of clinical guidance drawn from high-quality evidence proposing interventions that could inform clinical practice and service development. This article was authored by Bagnana Cecilia Matissegwegg, Mike Bratcher, Michelle Maill, and others.