 CMG is a complex protein composed of 36 subunits that assembles and moves along the DNA during replication. It was previously thought that CMG moved along the DNA via diffusion or by unidirectional translocation. However, recent research suggests that CMG moves along the DNA by both methods simultaneously. This new finding provides insight into how CMG interacts with the DNA and could help scientists better understand the process of DNA replication. This article was authored by Daniel Ramirez Montero, Humberto Sanchez, Eddo Van Veen and others.