 This study found that chitosan has a buffering effect on the pH of CUNIT orthodontic archwire when immersed in artificial saliva and 2% chitosan. It also demonstrated that chitosan has a lower copper ion release rate compared to CUNIT orthodontic archwire alone. Additionally, the surface roughness of the chitosan-treated wire was better than the untreated wire. This article was authored by I.K.A. Devy, Earl Yara-Suffronap, Fina, and others.