 This study investigated the effects of continuous epidural infusions of lidocaine on the development of neuropathic pain following spinal nerve ligation. The results showed that continuous epidural infusions of lidocaine significantly reduced the development of mechanical allodinia and decreased inflammation in the spinal cord. Furthermore, the effectiveness of lidocaine was independent of when it was administered, the drug was equally effective regardless of whether it was given before or after the initiation of the spinal nerve ligation. This article was authored by Yuzhan Chong, Min-suk Kim, Nam-yoon Kim, and others.