 The study examined the role of 19 different Argonaut, AGO, proteins in the nematoceno-hobditis elegans. These proteins are responsible for regulating gene expression by interacting with small non-coding RNAs, SNC RNAs. Using CISPR-Cas9 technology, researchers were able to tag these proteins with fluorescent markers and observed their expression patterns during development. They also observed how the absence of certain AGOs affected SNC RNA levels and developmental processes. This allowed them to identify specific roles for each protein and determine how they interact with other proteins to control gene expression. Additionally, they found that some AGOs are involved in stress responses and pathogen defense, suggesting that they may play important roles in maintaining homeostasis. This article was authored by Yuri Sarusi, Andrew Lugoski, Lena Wadi, and others.