 This study found that graduate courses in clinical and translational science, CTS, tend to cover many statistical fundamentals, but there are still some areas where learning gaps exist. These include understanding the implications of selecting appropriate statistical methods, understanding the purpose of meta-analysis, and the use of early stopping rules in clinical trials. To address these gaps, educational materials should be developed to help fill them. This article was authored by Robert A. Oster, Katrina Aldevic, Sally W. Thurston, and others.