 The estimated prevalence of esophageal atresia, EA, in the Sao Paulo state, SPS, population database has increased from 2005 to 2018, with the highest prevalence rate in the group with maternal age of greater than or equal to 35 years. No seasonality was observed. This article was authored by Emilio Freita Silvestri, Eduardo Jamilfarra Oliveira, Mossella Cheed, and others.