 Gastric cancer is a deadly and common cancer worldwide, with stomach cancer being the fifth most common neoplasm and the third most deadly cancer, resulting in an estimated 783,000 deaths in 2018. The incidence and mortality of gastric cancer are highly variable by region and dependent on diet and helicobacter pylori infection. While preventing and treating age pylori infection has decreased the overall incidence of gastric cancer, it has also contributed to an increase in cardiac gastric cancer. A better understanding of the ideology and risk factors of the disease can help approach age pylori infection. Dietary modification, smoking cessation, exercise, and genetic testing hold promise in preventing gastric cancer while earlier diagnosis through genetic testing increases survival. This article was authored by Prashant Rala and Adam Barsuk.